Founding a new human population

I’m very pleased have another query to answer from a listener to More or Less. And what a great question:

BlofeldI am embarking on a Career as a James Bond baddie, and I want to make sure everything is very carefully planned.  I am under no illusions that Commander Bond will thwart my first efforts to take over the world, however I am keen to become a recurring character, and that’s where you come in.

I intend to escape from Mr Bond at the last minute and I intend to populate an island or other planet, depending on budget.  However I am not clear how many men and how many women I will need to take with me to ensure we do not have issues with inbreeding in the population creating genetic disorders and the like.  How many people do you need to create a new race of people?

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